ARTHROBEN® contains a blend of natural bioflavonoids, which provides comprehensive and balanced inhibition of three metabolic pathways (COX-1, COX-2, 5-LOX) unlike NSAIDs, which cause strong selective inhibition of a single individual inflammatory pathway. This well-balanced method of action helps minimize systemic side effects, making it gentle on the gastrointestinal tract while effectively managing the metabolic imbalances of osteoarthritis (OA). ARTHROBEN® also offers two variants of hydrolyzed collagen that stimulate anabolic processes in connective tissues and inhibit various catabolic enzymes to help stimulate the repair process.